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Elevated Norepinephrine Metabolism Gauges Alzheimer’s Disease-Related Pathology and Memory Decline

The noradrenergic (NE) locus coeruleus (LC) is vulnerable to hyperphosphorylated tau, and dysregulated NE-metabolism is linked to greater tau and disease progression. We investigated whether elevated NE-metabolism alone predicts memory decline or whether concomitant presence of tau and amyloid-β is...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Riphagen, Joost M., van Egroo, Maxime, Jacobs, Heidi I.L.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075385/
https://ncbi.nlm.nih.gov/pubmed/33554915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-201411
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