A Systems Biology Approach for Hypothesizing the Effect of Genetic Variants on Neuroimaging Features in Alzheimer’s Disease

BACKGROUND: Neuroimaging markers provide quantitative insight into brain structure and function in neurodegenerative diseases, such as Alzheimer’s disease, where we lack mechanistic insights to explain pathophysiology. These mechanisms are often mediated by genes and genetic variations and are often...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Golriz Khatami, Sepehr, Domingo-Fernández, Daniel, Mubeen, Sarah, Hoyt, Charles Tapley, Robinson, Christine, Karki, Reagon, Iyappan, Anandhi, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075382/
https://ncbi.nlm.nih.gov/pubmed/33554913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-201397
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