A Systems Biology Approach for Hypothesizing the Effect of Genetic Variants on Neuroimaging Features in Alzheimer’s Disease

BACKGROUND: Neuroimaging markers provide quantitative insight into brain structure and function in neurodegenerative diseases, such as Alzheimer’s disease, where we lack mechanistic insights to explain pathophysiology. These mechanisms are often mediated by genes and genetic variations and are often...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Golriz Khatami, Sepehr, Domingo-Fernández, Daniel, Mubeen, Sarah, Hoyt, Charles Tapley, Robinson, Christine, Karki, Reagon, Iyappan, Anandhi, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075382/
https://ncbi.nlm.nih.gov/pubmed/33554913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-201397
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