Sodium zirconium cyclosilicate increases serum bicarbonate concentrations among patients with hyperkalaemia: exploratory analyses from three randomized, multi-dose, placebo-controlled trials

BACKGROUND: Sodium zirconium cyclosilicate (SZC) binds potassium and ammonium in the gastrointestinal tract. In addition to serum potassium reduction, Phase 2 trial data have shown increased serum bicarbonate with SZC, which may be clinically beneficial because maintaining serum bicarbonate ≥22 mmol...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Roger, Simon D, Spinowitz, Bruce S, Lerma, Edgar V, Fishbane, Steven, Ash, Stephen R, Martins, Julian G, Quinn, Carol Moreno, Packham, David K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075377/
https://ncbi.nlm.nih.gov/pubmed/32588050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfaa158
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