Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage

We recently reported that isoflurane conditioning provided multifaceted protection against subarachnoid hemorrhage (SAH)-induced delayed cerebral ischemia (DCI), and this protection was through the upregulation of endothelial nitric oxide synthase (eNOS). SIRT1, an NAD-dependent deacetylase, was sho...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Liu, Meizi, Jayaraman, Keshav, Giri, Tusar, Zipfel, Gregory J., Athiraman, Umeshkumar
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074752/
https://ncbi.nlm.nih.gov/pubmed/33924243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084291
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