Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

Type I interferons (IFNs) are our first line of defense against virus infection. Recent studies have suggested the ability of SARS-CoV-2 proteins to inhibit IFN responses. Emerging data also suggest that timing and extent of IFN production is associated with manifestation of COVID-19 severity. In sp...

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Publicado no:iScience
Main Authors: Banerjee, Arinjay, El-Sayes, Nader, Budylowski, Patrick, Jacob, Rajesh Abraham, Richard, Daniel, Maan, Hassaan, Aguiar, Jennifer A., Demian, Wael L., Baid, Kaushal, D'Agostino, Michael R., Ang, Jann Catherine, Murdza, Tetyana, Tremblay, Benjamin J.-M., Afkhami, Sam, Karimzadeh, Mehran, Irving, Aaron T., Yip, Lily, Ostrowski, Mario, Hirota, Jeremy A., Kozak, Robert, Capellini, Terence D., Miller, Matthew S., Wang, Bo, Mubareka, Samira, McGeer, Allison J., McArthur, Andrew G., Doxey, Andrew C., Mossman, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074517/
https://ncbi.nlm.nih.gov/pubmed/33937724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102477
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