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Interleukin-1 blockade with RPH-104 in patients with acute ST-elevation myocardial infarction: study design and rationale

BACKGROUND: Myocardial injury of ST-segment elevation myocardial infarction (STEMI) initiates an intense inflammatory response that contributes to further damage and is a predictor of increased risk of death or heart failure (HF). Interleukin-1 (IL-1) is a key mediator of local and systemic inflamma...

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Publicat a:J Transl Med
Autors principals: Samsonov, M., Bogin, V., Van Tassell, B. W., Abbate, A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074403/
https://ncbi.nlm.nih.gov/pubmed/33902621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02828-z
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