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In Silico Selection and Evaluation of Pugnins with Antibacterial and Anticancer Activity Using Skin Transcriptome of Treefrog (Boana pugnax)

In order to combat bacterial and cancer resistance, we identified peptides (pugnins) with dual antibacterial l–anticancer activity from the Boana pugnax (B. pugnax) skin transcriptome through in silico analysis. Pugnins A and B were selected owing to their high similarity to the DS4.3 peptide, which...

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Библиографические подробности
Опубликовано в: :Pharmaceutics
Главные авторы: Liscano, Yamil, Medina, Laura, Oñate-Garzón, Jose, Gúzman, Fanny, Pickholz, Monica, Delgado, Jean Paul
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074116/
https://ncbi.nlm.nih.gov/pubmed/33919639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040578
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