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In Silico Selection and Evaluation of Pugnins with Antibacterial and Anticancer Activity Using Skin Transcriptome of Treefrog (Boana pugnax)

In order to combat bacterial and cancer resistance, we identified peptides (pugnins) with dual antibacterial l–anticancer activity from the Boana pugnax (B. pugnax) skin transcriptome through in silico analysis. Pugnins A and B were selected owing to their high similarity to the DS4.3 peptide, which...

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Bibliografski detalji
Izdano u:Pharmaceutics
Glavni autori: Liscano, Yamil, Medina, Laura, Oñate-Garzón, Jose, Gúzman, Fanny, Pickholz, Monica, Delgado, Jean Paul
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074116/
https://ncbi.nlm.nih.gov/pubmed/33919639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040578
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