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In Silico Selection and Evaluation of Pugnins with Antibacterial and Anticancer Activity Using Skin Transcriptome of Treefrog (Boana pugnax)

In order to combat bacterial and cancer resistance, we identified peptides (pugnins) with dual antibacterial l–anticancer activity from the Boana pugnax (B. pugnax) skin transcriptome through in silico analysis. Pugnins A and B were selected owing to their high similarity to the DS4.3 peptide, which...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Liscano, Yamil, Medina, Laura, Oñate-Garzón, Jose, Gúzman, Fanny, Pickholz, Monica, Delgado, Jean Paul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074116/
https://ncbi.nlm.nih.gov/pubmed/33919639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040578
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