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Platyphyllenone Induces Autophagy and Apoptosis by Modulating the AKT and JNK Mitogen-Activated Protein Kinase Pathways in Oral Cancer Cells

Platyphyllenone is a type of diarylheptanoid that exhibits anti-inflammatory and chemoprotective effects. However, its effect on oral cancer remains unclear. In this study, we investigated whether platyphyllenone can promote apoptosis and autophagy in SCC-9 and SCC-47 cells. We found that it dose-de...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Liu, Yen-Tze, Ho, Hsin-Yu, Lin, Chia-Chieh, Chuang, Yi-Ching, Lo, Yu-Sheng, Hsieh, Ming-Ju, Chen, Mu-Kuan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074098/
https://ncbi.nlm.nih.gov/pubmed/33921647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084211
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