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Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase

The human enzyme D-3-phosphoglycerate dehydrogenase (hPHGDH) catalyzes the reversible dehydrogenation of 3-phosphoglycerate (3PG) into 3-phosphohydroxypyruvate (PHP) using the NAD(+)/NADH redox cofactor, the first step in the phosphorylated pathway producing L-serine. We focused on the full-length e...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Murtas, Giulia, Marcone, Giorgia Letizia, Peracchi, Alessio, Zangelmi, Erika, Pollegioni, Loredano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073719/
https://ncbi.nlm.nih.gov/pubmed/33921788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084231
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