A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53

Long noncoding RNAs (lncRNA) have been associated with various types of cancer; however, the precise role of many lncRNAs in tumorigenesis remains elusive. Here we demonstrate that the cytosolic lncRNA P53RRA is downregulated in cancers and functions as a tumor suppressor by inhibiting cancer progre...

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Pubblicato in:Cancer Res
Autori principali: Mao, Chao, Wang, Xiang, Liu, Yating, Wang, Min, Yan, Bin, Jiang, Yiqun, Shi, Ying, Shen, Yi, Liu, Xiaoli, Lai, Weiwei, Yang, Rui, Xiao, Desheng, Cheng, Yan, Liu, Shuang, Zhou, Hu, Cao, Ya, Yu, Weishi, Muegge, Kathrin, Yu, Herbert, Tao, Yongguang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073197/
https://ncbi.nlm.nih.gov/pubmed/29588351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3454
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