Protective Role of a TMPRSS2 Variant on Severe COVID-19 Outcome in Young Males and Elderly Women

The protease encoded by the TMPRSS2 gene facilitates viral infections and has been implicated in the pathogenesis of SARS-CoV-2. We analyzed the TMPRSS2 sequence and correlated the protein variants with the clinical features of a cohort of 1177 patients affected by COVID-19 in Italy. Nine relatively...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Genes (Basel)
Auteurs principaux: Monticelli, Maria, Hay Mele, Bruno, Benetti, Elisa, Fallerini, Chiara, Baldassarri, Margherita, Furini, Simone, Frullanti, Elisa, Mari, Francesca, Andreotti, Giuseppina, Cubellis, Maria Vittoria, Renieri, Alessandra
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073081/
https://ncbi.nlm.nih.gov/pubmed/33921689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12040596
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