Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms

High-grade Gastroenteropancreatic Neuroendocrine neoplasms (H-NENs) comprehend well-differentiated tumors (NET G3) and poorly differentiated carcinomas (NEC) with proliferative activity indexes as mitotic count (MC) >20 mitoses/10 HPF and Ki-67 >20%. At present, no specific therapy for H-NENs...

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Publicado en:J Clin Med
Main Authors: Centonze, Giovanni, Lagano, Vincenzo, Sabella, Giovanna, Mangogna, Alessandro, Garzone, Giovanna, Filugelli, Martina, Belmonte, Beatrice, Cattaneo, Laura, Crisafulli, Valentina, Pellegrinelli, Alessio, Simbolo, Michele, Scarpa, Aldo, Spaggiari, Paola, Brambilla, Tatiana, Pusceddu, Sara, Prinzi, Natalie, Anichini, Andrea, Tripodo, Claudio, Milione, Massimo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072982/
https://ncbi.nlm.nih.gov/pubmed/33920514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10081741
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