Citric Acid Cycle Metabolites Predict Infarct Size in Pigs Submitted to Transient Coronary Artery Occlusion and Treated with Succinate Dehydrogenase Inhibitors or Remote Ischemic Perconditioning

Succinate dehydrogenase (SDH) inhibition with malonate during reperfusion reduced myocardial infarction in animals, whereas its endogenous substrate, succinate, is detected in plasma from STEMI patients. We investigated whether protection by SDH inhibition is additive to that of remote ischemic perc...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Consegal, Marta, Núñez, Norberto, Barba, Ignasi, Benito, Begoña, Ruiz-Meana, Marisol, Inserte, Javier, Ferreira-González, Ignacio, Rodríguez-Sinovas, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072915/
https://ncbi.nlm.nih.gov/pubmed/33923786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084151
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