Recombinant Pseudorabies Virus with TK/gE Gene Deletion and Flt3L Co-Expression Enhances the Innate and Adaptive Immune Response via Activating Dendritic Cells

Owing to viral evolution and recombination, emerging pseudorabies virus (PRV) strains have caused unprecedented outbreaks in swine farms even when the pigs were previously vaccinated, which might indicate that traditional vaccines were unable to provide effective protection. The development of safe...

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Vydáno v:Viruses
Hlavní autoři: Yao, Lun, Hu, Qiao, Chen, Siqi, Zhou, Tong, Yu, Xuexiang, Ma, Hailong, H. Ghonaim, Ahmed., Wu, Hao, Sun, Qi, Fan, Shengxian, He, Qigai
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072707/
https://ncbi.nlm.nih.gov/pubmed/33923590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13040691
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