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A model for a partnership of lipid transfer proteins and scramblases in membrane expansion and organelle biogenesis

The autophagy protein ATG2, proposed to transfer bulk lipid from the endoplasmic reticulum (ER) during autophagosome biogenesis, interacts with ER residents TMEM41B and VMP1 and with ATG9, in Golgi-derived vesicles that initiate autophagosome formation. In vitro assays reveal TMEM41B, VMP1, and ATG9...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Ghanbarpour, Alireza, Valverde, Diana P., Melia, Thomas J., Reinisch, Karin M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072408/
https://ncbi.nlm.nih.gov/pubmed/33850023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2101562118
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