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NLRP3 Inflammasome: A Promising Therapeutic Target for Drug-Induced Toxicity

Drug-induced toxicity, which impairs human organ function, is a serious problem during drug development that hinders the clinical use of many marketed drugs, and the underlying mechanisms are complicated. As a sensor of infections and external stimuli, nucleotide-binding oligomerization domain (NOD)...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Wei, Shanshan, Ma, Wanjun, Zhang, Bikui, Li, Wenqun
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072389/
https://ncbi.nlm.nih.gov/pubmed/33912556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.634607
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