The Production of Testosterone and Gene Expression in Neonatal Testes of Rats Exposed to Diisoheptyl Phthalate During Pregnancy is Inhibited

Background: Diisoheptyl phthalate (DIHP) is a phthalate plasticizer, which is a branched phthalate. Here, we reported the effects of gestational exposure to DIHP on testis development in male rats. Methods: Pregnant Sprague-Dawley rats were orally fed with vehicle (corn oil, control) or DIHP (10, 10...

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Vydáno v:Front Pharmacol
Hlavní autoři: Ji, Bin, Wen, Zina, Ni, Chaobo, Zhu, Qiqi, Wang, Yiyan, Li, Xiaoheng, Zhong, Ying, Ge, Ren-Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072358/
https://ncbi.nlm.nih.gov/pubmed/33912029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.568311
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