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Ginkgolide B-induced AMPK pathway activation protects astrocytes by regulating endoplasmic reticulum stress, oxidative stress and energy metabolism induced by Aβ(1-42)

Ginkgolide B (GB), the diterpenoid lactone compound isolated from the extracts of Ginkgo biloba leaves, significantly improves cognitive impairment, but its potential pharmacological effect on astrocytes induced by β-amyloid (Aβ)(1-42) remains to be elucidated. The present study aimed to investigate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med Rep
Hauptverfasser: Wang, Jing, Ding, Yan, Zhuang, Linwu, Wang, Zhenzhong, Xiao, Wei, Zhu, Jingbo
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072312/
https://ncbi.nlm.nih.gov/pubmed/33880582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12096
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