Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury

Fibroblast growth factor 23 (FGF23), a hormone generally derived from bone, is important in phosphate and vitamin D homeostasis. In acute kidney injury (AKI) patients, high-circulating FGF23 levels are associated with disease progression and mortality. However, the organ and cell type of FGF23 produ...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Radhakrishnan, Kamalakannan, Kim, Yong-Hoon, Jung, Yoon Seok, Kim, Don-Kyu, Na, Soon-Young, Lim, Daejin, Kim, Dong Hun, Kim, Jina, Kim, Hyung-Seok, Choy, Hyon E., Cho, Sung Jin, Lee, In-Kyu, Ayvaz, Şamil, Nittka, Stefanie, Fliser, Danilo, Schunk, Stefan J., Speer, Thimoteus, Dooley, Steven, Lee, Chul-Ho, Choi, Hueng-Sik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072258/
https://ncbi.nlm.nih.gov/pubmed/33853949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022841118
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