Hippocampal astrocytic neogenin regulating glutamate uptake, a critical pathway for preventing epileptic response

Epilepsy, a common neurological disorder, is featured with recurrent seizures. Its underlying pathological mechanisms remain elusive. Here, we provide evidence for loss of neogenin (NEO1), a coreceptor for multiple ligands, including netrins and bone morphological proteins, in the development of epi...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Sun, Dong, Tan, Zhi-Bing, Sun, Xiang-Dong, Liu, Zhi-Peng, Chen, Wen-Bing, Milibari, Leena, Ren, Xiao, Yao, Ling-Ling, Lee, Daehoon, Shen, Chen, Pan, Jin-Xiu, Huang, Zhi-Hui, Mei, Lin, Xiong, Wen-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072226/
https://ncbi.nlm.nih.gov/pubmed/33850017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022921118
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