Exploiting the Role of Hypoxia-Inducible Factor 1 and Pseudohypoxia in the Myelodysplastic Syndrome Pathophysiology

Myelodysplastic syndromes (MDS) comprise a heterogeneous group of clonal hematopoietic stem (HSCs) and/or progenitor cells disorders. The established dependence of MDS progenitors on the hypoxic bone marrow (BM) microenvironment turned scientific interests to the transcription factor hypoxia-inducib...

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Published in:Int J Mol Sci
Main Authors: Stergiou, Ioanna E., Kambas, Konstantinos, Poulaki, Aikaterini, Giannouli, Stavroula, Katsila, Theodora, Dimitrakopoulou, Aglaia, Vidali, Veroniki, Mouchtouris, Vasileios, Kloukina, Ismini, Xingi, Evangelia, Pagakis, Stamatis N., Probert, Lesley, Patrinos, George P., Ritis, Konstantinos, Tzioufas, Athanasios G., Voulgarelis, Michael
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071466/
https://ncbi.nlm.nih.gov/pubmed/33921064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084099
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