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The Antibiotic Doxycycline Impairs Cardiac Mitochondrial and Contractile Function
Tetracycline antibiotics act by inhibiting bacterial protein translation. Given the bacterial ancestry of mitochondria, we tested the hypothesis that doxycycline—which belongs to the tetracycline class—reduces mitochondrial function, and results in cardiac contractile dysfunction in cultured H9C2 ca...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8071362/ https://ncbi.nlm.nih.gov/pubmed/33921053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084100 |
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