Sildenafil 4.0—Integrated Synthetic Chemistry, Formulation and Analytical Strategies Effecting Immense Therapeutic and Societal Impact in the Fourth Industrial Era

Sildenafil is a potent selective, reversible inhibitor of phosphodiesterase type 5 (PDE5) approved for the treatment of erectile dysfunction and pulmonary arterial hypertension. Whilst twenty years have passed since its original approval by the US Food and Drug Administration (USFDA), sildenafil ent...

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Bibliografiske detaljer
Udgivet i:Pharmaceuticals (Basel)
Main Authors: Ouranidis, Andreas, Tsiaxerli, Anastasia, Vardaka, Elisavet, Markopoulou, Catherine K., Zacharis, Constantinos K., Nicolaou, Ioannis, Hatzichristou, Dimitris, Haidich, Anna-Bettina, Kostomitsopoulos, Nikolaos, Kachrimanis, Kyriakos
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071249/
https://ncbi.nlm.nih.gov/pubmed/33920975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14040365
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