Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors

A current trend in the quest for new therapies for complex, multifactorial diseases, such as diabetes mellitus (DM), is to find dual or even multi-target inhibitors. In DM, the sodium dependent glucose cotransporter 2 (SGLT2) in the kidneys and the glycogen phosphorylase (GP) in the liver are valida...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Sipos, Ádám, Szennyes, Eszter, Hajnal, Nikolett Éva, Kun, Sándor, Szabó, Katalin E., Uray, Karen, Somsák, László, Docsa, Tibor, Bokor, Éva
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071193/
https://ncbi.nlm.nih.gov/pubmed/33920838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14040364
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