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Mutations Q93H and E97K in TPM2 Disrupt Ca-Dependent Regulation of Actin Filaments
Tropomyosin is a two-chain coiled coil protein, which together with the troponin complex controls interactions of actin with myosin in a Ca(2+)-dependent manner. In fast skeletal muscle, the contractile actin filaments are regulated by tropomyosin isoforms Tpm1.1 and Tpm2.2, which form homo- and het...
Gespeichert in:
| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8070786/ https://ncbi.nlm.nih.gov/pubmed/33919826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084036 |
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