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Beneficial Effects of Cyclic Ether 2-Butoxytetrahydrofuran from Sea Cucumber Holothuria scabra against Aβ Aggregate Toxicity in Transgenic Caenorhabditis elegans and Potential Chemical Interaction

The pathological finding of amyloid-β (Aβ) aggregates is thought to be a leading cause of untreated Alzheimer’s disease (AD). In this study, we isolated 2-butoxytetrahydrofuran (2-BTHF), a small cyclic ether, from Holothuria scabra and demonstrated its therapeutic potential against AD through the at...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Tangrodchanapong, Taweesak, Sornkaew, Nilubon, Yurasakpong, Laphatrada, Niamnont, Nakorn, Nantasenamat, Chanin, Sobhon, Prasert, Meemon, Krai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070609/
https://ncbi.nlm.nih.gov/pubmed/33920352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082195
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