Reverse Engineering of Ewing Sarcoma Regulatory Network Uncovers PAX7 and RUNX3 as Master Regulators Associated with Good Prognosis

SIMPLE SUMMARY: Ewing Sarcoma is a rare cancer that, when localized, has an overall five-year survival rate of 70%. Patients with metastasis have a five-year survival rate of 15 to 30%. Early analysis of patient prognosis can be crucial to provide adequate treatment and increase chances of survival....

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Ribeiro-Dantas, Marcel da Câmara, Imparato, Danilo Oliveira, Dalmolin, Matheus Gibeke Siqueira, de Farias, Caroline Brunetto, Brunetto, André Tesainer, da Cunha Jaeger, Mariane, Roesler, Rafael, Sinigaglia, Marialva, Siqueira Dalmolin, Rodrigo Juliani
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070584/
https://ncbi.nlm.nih.gov/pubmed/33924679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081860
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