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α-Tocopherol Attenuates Oxidative Phosphorylation of CD34(+) Cells, Enhances Their G0 Phase Fraction and Promotes Hematopoietic Stem and Primitive Progenitor Cell Maintenance

Alpha tocopherol acetate (αTOA) is an analogue of alpha tocopherol (αTOC) that exists in the form of an injectable drug. In the context of the metabolic hypothesis of stem cells, we studied the impact of αTOA on the metabolic energetic profile and functional properties of hematopoietic stem and prog...

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Publicat a:Biomolecules
Autors principals: Rodriguez, Laura, Duchez, Pascale, Touya, Nicolas, Debeissat, Christelle, Guitart, Amélie V., Pasquet, Jean-Max, Vlaski-Lafarge, Marija, Brunet de la Grange, Philippe, Ivanovic, Zoran
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070309/
https://ncbi.nlm.nih.gov/pubmed/33920203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040558
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