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Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets

SIMPLE SUMMARY: All cancers must maintain telomere length to achieve immortality and around 80% do so by reactivating the enzyme complex telomerase. The diverse regulatory mechanisms surrounding the enzymatic component, telomerase reverse transcriptase (TERT), are often exploited during tumorigenesi...

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Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autori: Subasri, Mathushan, Shooshtari, Parisa, Watson, Andrew J., Betts, Dean H.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070023/
https://ncbi.nlm.nih.gov/pubmed/33924498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081853
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