Chronic Ouabain Prevents Na,K-ATPase Dysfunction and Targets AMPK and IL-6 in Disused Rat Soleus Muscle

Sustained sarcolemma depolarization due to loss of the Na,K-ATPase function is characteristic for skeletal muscle motor dysfunction. Ouabain, a specific ligand of the Na,K-ATPase, has a circulating endogenous analogue. We hypothesized that the Na,K-ATPase targeted by the elevated level of circulatin...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kravtsova, Violetta V., Paramonova, Inna I., Vilchinskaya, Natalia A., Tishkova, Maria V., Matchkov, Vladimir V., Shenkman, Boris S., Krivoi, Igor I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069997/
https://ncbi.nlm.nih.gov/pubmed/33920198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083920
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