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Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19

Pluripotent stem cells can be stabilized in vitro at different developmental states by the use of specific chemicals and soluble factors. The naïve and primed states are the best characterized pluripotency states. Naïve pluripotent stem cells (PSCs) correspond to the early pre-implantation blastocys...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Bernad, Raquel, Lynch, Cian J., Urdinguio, Rocio G., Stephan-Otto Attolini, Camille, Fraga, Mario F., Serrano, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069959/
https://ncbi.nlm.nih.gov/pubmed/33921436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040876
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