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Octreotide and Pasireotide Combination Treatment in Somatotroph Tumor Cells: Predominant Role of SST(2) in Mediating Ligand Effects
SIMPLE SUMMARY: First-generation somatostatin receptor ligands, such as octreotide, are the first-line medical therapy in acromegaly. Octreotide shows preferential binding for somatostatin receptor subtype 2 (SST(2)), while the second-generation ligand, pasireotide, has high affinity for multiple SS...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8069349/ https://ncbi.nlm.nih.gov/pubmed/33920241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081816 |
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