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Antioxidant thioether core-crosslinked nanoparticles prevent the bilateral spread of secondary injury to protect spatial learning and memory in a controlled cortical impact mouse model of traumatic brain injury

The secondary phase of traumatic brain injury (TBI) is partly caused by the release of excess reactive oxygen species (ROS) from the primary injury. However, there are currently no therapies that have been shown to reduce the secondary spread of injury beyond the primary insult. Nanoparticles offer...

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Foilsithe in:Biomaterials
Main Authors: Tarudji, Aria W., Gee, Connor C., Romereim, Sarah M., Convertine, Anthony J., Kievit, Forrest M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068673/
https://ncbi.nlm.nih.gov/pubmed/33819812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2021.120766
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