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Presynaptic store-operated Ca(2+) entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress
Store operated calcium entry (SOCE) is activated by depletion of Ca(2+) from the endoplasmic reticulum (ER) and mediated by stromal interaction molecule (STIM) proteins. Here, we show that in rat and mouse hippocampal neurons acute ER Ca(2+) depletion increases presynaptic Ca(2+) levels and glutamat...
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| Publicado no: | Neuron |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8068669/ https://ncbi.nlm.nih.gov/pubmed/33711258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2021.02.023 |
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