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Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma
Background Precision medicine and drug repurposing are attractive strategies, especially for tumors with worse prognosis. Glioblastoma is a highly malignant brain tumor with limited treatment options and short survival times. We identified novel BRAF (47-438del) and PIK3R1 (G376R) mutations in a gli...
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| Publicat a: | Invest New Drugs |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer US
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8068653/ https://ncbi.nlm.nih.gov/pubmed/33313992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-020-01037-7 |
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