(177)Lu-labeled low-molecular-weight agents for PSMA-targeted radiopharmaceutical therapy

PURPOSE: To develop a prostate-specific membrane antigen (PSMA)-targeted radiotherapeutic for metastatic castration-resistant prostate cancer (mCRPC) with optimized efficacy and minimized toxicity employing the β-particle radiation of (177)Lu. METHODS: We synthesized 14 new PSMA-targeted, (177)Lu-la...

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Udgivet i:Eur J Nucl Med Mol Imaging
Main Authors: Banerjee, Sangeeta Ray, Kumar, Vivek, Lisok, Ala, Chen, Jian, Minn, Il, Brummet, Mary, Boinapally, Srikanth, Cole, Michael, Ngen, Ethel, Wharram, Bryan, Brayton, Cory, Hobbs, Robert F., Pomper, Martin G.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068522/
https://ncbi.nlm.nih.gov/pubmed/31399803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-019-04434-0
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