Transmissible α-synuclein seeding activity in brain and stomach of patients with Parkinson’s disease

Cerebral deposition of abnormally aggregated α-synuclein (αSyn) is a neuropathological hallmark of Parkinson’s disease (PD). PD-associated αSyn (αSyn(PD)) aggregates can act as proteinaceous nuclei (“seeds”) able of self-templated propagation. Since this is strikingly reminiscent to properties of pr...

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Vydáno v:Acta Neuropathol
Hlavní autoři: Thomzig, Achim, Wagenführ, Katja, Pinder, Phillip, Joncic, Marion, Schulz-Schaeffer, Walter J., Beekes, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2021
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068459/
https://ncbi.nlm.nih.gov/pubmed/33895878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-021-02312-4
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