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Understand KRAS and the Quest for Anti-Cancer Drugs
The KRAS oncogene is mutated in approximately ~30% of human cancers, and the targeting of KRAS has long been highlighted in many studies. Nevertheless, attempts to target KRAS directly have been ineffective. This review provides an overview of the structure of KRAS and its characteristic signaling p...
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| Publicado no: | Cells |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8068306/ https://ncbi.nlm.nih.gov/pubmed/33917906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040842 |
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