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Novel Pyrimidine Derivatives as Potential Anticancer Agents: Synthesis, Biological Evaluation and Molecular Docking Study

In the present paper, new pyrimidine derivatives were designed, synthesized and analyzed in terms of their anticancer properties. The tested compounds were evaluated in vitro for their antitumor activity. The cytotoxic effect on normal human dermal fibroblasts (NHDF) was also determined. According t...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Tylińska, Beata, Wiatrak, Benita, Czyżnikowska, Żaneta, Cieśla-Niechwiadowicz, Aneta, Gębarowska, Elżbieta, Janicka-Kłos, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067809/
https://ncbi.nlm.nih.gov/pubmed/33917090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083825
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