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Development of Covalent Chitosan-Polyethylenimine Derivatives as Gene Delivery Vehicle: Synthesis, Characterization, and Evaluation

There is an increasing interest in cationic polymers as important constituents of non-viral gene delivery vectors. In the present study, we developed a versatile synthetic route for the production of covalent polymeric conjugates consisting of water-soluble depolymerized chitosan (dCS; M(W) 6–9 kDa)...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Nicolle, Laura, Casper, Jens, Willimann, Melanie, Journot, Céline M. A., Detampel, Pascal, Einfalt, Tomaž, Grisch-Chan, Hiu Man, Thöny, Beat, Gerber-Lemaire, Sandrine, Huwyler, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067803/
https://ncbi.nlm.nih.gov/pubmed/33917124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083828
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