Pancreatic Cancer Signaling Pathways, Genetic Alterations, and Tumor Microenvironment: The Barriers Affecting the Method of Treatment

Genetic alterations, especially the K-Ras mutation, carry the heaviest burden in the progression of pancreatic precursor lesions into pancreatic ductal adenocarcinoma (PDAC). The tumor microenvironment is one of the challenges that hinder the therapeutic approaches from functioning sufficiently and...

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Bibliografski detalji
Izdano u:Biomedicines
Glavni autori: Javadrashid, Darya, Baghbanzadeh, Amir, Derakhshani, Afshin, Leone, Patrizia, Silvestris, Nicola, Racanelli, Vito, Solimando, Antonio Giovanni, Baradaran, Behzad
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067185/
https://ncbi.nlm.nih.gov/pubmed/33918146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040373
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