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pH Dependence of T(2) for Hyperpolarizable (13)C-Labelled Small Molecules Enables Spatially Resolved pH Measurement by Magnetic Resonance Imaging

Hyperpolarized (13)C magnetic resonance imaging often uses spin-echo-based pulse sequences that are sensitive to the transverse relaxation time T(2). In this context, local T(2)-changes might introduce a quantification bias to imaging biomarkers. Here, we investigated the pH dependence of the appare...

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Podrobná bibliografie
Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Grashei, Martin, Hundshammer, Christian, van Heijster, Frits H. A., Topping, Geoffrey J., Schilling, Franz
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067065/
https://ncbi.nlm.nih.gov/pubmed/33918366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14040327
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