Filociclovir Is an Active Antiviral Agent against Ocular Adenovirus Isolates In Vitro and in the Ad5/NZW Rabbit Ocular Model

Presently, there is no FDA- or EMA-approved antiviral for the treatment of human adenovirus (HAdV) ocular infections. This study determined the antiviral activity of filociclovir (FCV) against ocular HAdV isolates in vitro and in the Ad5/NZW rabbit ocular model. The 50% effective concentrations (EC(...

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發表在:Pharmaceuticals (Basel)
Main Authors: Romanowski, Eric G., Hussein, Islam T. M., Cardinale, Steven C., Butler, Michelle M., Morin, Lucas R., Bowlin, Terry L., Yates, Kathleen A., Shanks, Robert M. Q., Kowalski, Regis P.
格式: Artigo
語言:Inglês
出版: MDPI 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066960/
https://ncbi.nlm.nih.gov/pubmed/33810229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14040294
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