Adjuvants and Vaccines Used in Allergen-Specific Immunotherapy Induce Neutrophil Extracellular Traps

Aluminum hydroxide (alum) and monophosphoryl-lipid A (MPLA) are conventional adjuvants in vaccines for allergen-specific immunotherapy (AIT). Alum triggers the release of neutrophil extracellular traps (NETs) by neutrophils. NETs contain expelled decondensed chromatin associated with granular materi...

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Bibliographic Details
Published in:Vaccines (Basel)
Main Authors: Karacs, Jasmine, Reithofer, Manuel, Kitzmüller, Claudia, Kraller, Markus, Schmalz, Stefanie, Bleichert, Sonja, Huppa, Johannes B., Stockinger, Hannes, Bohle, Barbara, Jahn-Schmid, Beatrice
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066953/
https://ncbi.nlm.nih.gov/pubmed/33915724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9040321
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