A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer

Colorectal cancer (CRC) shows one of the largest proportions of familial cases among different malignancies, but only 5–10% of all CRC cases are linked to mutations in established predisposition genes. Thus, familial CRC constitutes a promising target for the identification of novel, high- to modera...

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Publicado no:J Pers Med
Principais autores: Skopelitou, Diamanto, Miao, Beiping, Srivastava, Aayushi, Kumar, Abhishek, Kuświk, Magdalena, Dymerska, Dagmara, Paramasivam, Nagarajan, Schlesner, Matthias, Lubiński, Jan, Hemminki, Kari, Försti, Asta, Bandapalli, Obul Reddy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066297/
https://ncbi.nlm.nih.gov/pubmed/33916261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11040262
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