Eltrombopag Improves Erythroid Differentiation in a Human Induced Pluripotent Stem Cell Model of Diamond Blackfan Anemia

Diamond Blackfan Anemia (DBA) is a congenital macrocytic anemia associated with ribosomal protein haploinsufficiency. Ribosomal dysfunction delays globin synthesis, resulting in excess toxic free heme in erythroid progenitors, early differentiation arrest, and pure red cell aplasia. In this study, D...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Qanash, Husam, Li, Yongqin, Smith, Richard H., Linask, Kaari, Young-Baird, Sara, Hakami, Waleed, Keyvanfar, Keyvan, Choy, John S., Zou, Jizhong, Larochelle, Andre
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065708/
https://ncbi.nlm.nih.gov/pubmed/33810313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040734
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker