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ICOS signaling limits regulatory T cell accumulation and function in visceral adipose tissue
A unique population of Foxp3(+) regulatory T cells (T(R)s) resides in visceral adipose tissue (VAT) that regulates adipose inflammation and helps preserve insulin sensitivity. Inducible T cell co-stimulator (ICOS) is highly expressed on effector (e)T(R)s that migrate to nonlymphoid tissues, and cont...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8065270/ https://ncbi.nlm.nih.gov/pubmed/33881452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201142 |
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