Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells

Arginine plays diverse roles in cellular physiology. As a semi-essential amino acid, arginine deprivation has been used to target cancers with arginine synthesis deficiency. Arginine-deprived cancer cells exhibit mitochondrial dysfunction, transcriptional reprogramming and eventual cell death. In th...

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Publicado no:Nat Commun
Main Authors: Chen, Chia-Lin, Hsu, Sheng-Chieh, Chung, Tan-Ya, Chu, Cheng-Ying, Wang, Hung-Jung, Hsiao, Pei-Wen, Yeh, Shauh-Der, Ann, David K., Yen, Yun, Kung, Hsing-Jien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065123/
https://ncbi.nlm.nih.gov/pubmed/33893278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22652-9
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