Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses

Rare protein-truncating variants (PTVs) in PALB2 confer increased risk to breast cancer, but relatively few studies have reported the characteristics of tumours with PALB2 PTVs. In this study, we describe molecular characteristics of tumours with either germline or somatic alterations in PALB2. DNA...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:NPJ Breast Cancer
Main Authors: Ng, Pei Sze, Pan, Jia Wern, Ahmad Zabidi, Muhammad Mamduh, Rajadurai, Pathmanathan, Yip, Cheng Har, Reuda, Oscar M., Dunning, Alison M., Antoniou, Antonis C., Easton, Douglas F., Caldas, Carlos, Chin, Suet-Feung, Teo, Soo Hwang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065101/
https://ncbi.nlm.nih.gov/pubmed/33893315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-021-00254-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados