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Immunogenomics guided design of immunomodulatory multi-epitope subunit vaccine against the SARS-CoV-2 new variants, and its validation through in silico cloning and immune simulation

Reports of the novel and more contagious strains of SARS-CoV-2 originating in different countries have further aggravated the pandemic situation. The recent substitutions in spike protein may be critical for the virus to evade the host's immune system and therapeutics that have already been dev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Comput Biol Med
Hauptverfasser: Khan, Abbas, Khan, Shahzeb, Saleem, Shoaib, Nizam-Uddin, N., Mohammad, Anwar, Khan, Taimoor, Ahmad, Sajjad, Arshad, Muhammad, Ali, Syed Shujait, Suleman, Muhammad, Wei, Dong-Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Published by Elsevier Ltd. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064902/
https://ncbi.nlm.nih.gov/pubmed/33930764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiomed.2021.104420
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